The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer Early Detection provide recommendations for prostate cancer screening in healthy men who have elected to participate in an early detection program. These treatment guidelines suggest what the best practice is for cancer care. • Initial prostate cancer diagnosis, added a footnote linking to the NCCN Guidelines for Prostate Cancer Early Detection. Tanya Dorff joins Alicia Morgans discussing recent updates to the NCCN guidelines for systemic therapies in the treatment of M1 prostate cancer. 2021 Jan 6;11(1):3. doi: 10.1186/s13550-020-00745-8. The NCCN Guidelines for Prostate Cancer provide multidisciplinary recommendations on the clinical management of patients with prostate cancer. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Prostate Cancer Prostatic Dis. NEW YORK (GenomeWeb) – The National Comprehensive Cancer Network issued updated prostate cancer guidelines that include new information about the role of family history, mutations in DNA repair genes, and testing for microsatellite instability and mismatch repair status for potential treatment with the Merck drug Keytruda (pembrolizumab). Upon completion of this activity, participants will be able to: Supported by educational grants from ARIAD Pharmaceuticals, Inc.; Bayer HealthCare Pharmaceuticals Inc.; CELGENE CORPORATION; Eisai Inc.; Endo Pharmaceuticals and HealthTronics; Genentech; Millennium: The Takeda Oncology Company; and Teva Pharmaceuticals. Kuten J, Dekalo S, Mintz I, Yossepowitch O, Mano R, Even-Sapir E. EJNMMI Res. The portions of the guidelines included herein focus on the roles of germline and somatic genetic testing, risk stratification with nomograms and tumor multigene molecular testing, androgen deprivation therapy, secondary hormonal therapy, chemotherapy, and immunotherapy in patients with prostate cancer. The NCCN Guidelines for Patients address disease types accounting for approximately 94% of all cancer diagnoses in the United States, including breast, colon, pancreatic, prostate, plus topics like supportive care and prevention.They are updated and expanded on a regular basis and have been translated into nine different languages. The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis, risk stratification and workup, treatment options for localized disease, and management of recurrent and advanced disease for clinicians who treat patients with prostate cancer. J Natl Compr Canc Netw. The Prostate Cancer Foundation is the world’s leading philanthropic organization dedicated to funding life-saving cancer research. The NCCN Prostate Cancer Panel also revised recommendations on the choice of intermittent or continuous androgen deprivation therapy based on recent phase III clinical data comparing the 2 strategies in the nonmetastatic and metastatic settings. Mustafa M, Rass HA, Yahya M, Hamdan K, Eiss Y. Further, the guideline recommendations for men with newly diagnosed prostate cancer have been expanded beyond consideration of Decipher Prostate Biopsy in low and favorable intermediate risk disease to now include unfavorable intermediate and high risk prostate cancer. Specifically, early detection strategies that do not recognize the importance of refined and selective treatment may result in harm. Recommendations for germline testing, molecular testing, and initial therapy have been developed for each risk category, each of which has its own management page in the newest version of the NCCN guidelines. By: Sarah Campen, PharmD Posted: Friday, September 28, 2018. Updated NCCN Guidelines for Prostate Cancer: New Treatment Options Added. Primary metastatic prostate cancer between prognosis or adequate/proper medical therapy. Mohler JL, Armstrong AJ, Bahnson RR, Boston B, Busby JE, D'Amico AV, Eastham JA, Enke CA, Farrington T, Higano CS, Horwitz EM, Kantoff PW, Kawachi MH, Kuettel M, Lee RJ, MacVicar GR, Malcolm AW, Miller D, Plimack ER, Pow-Sang JM, Roach M 3rd, Rohren E, Rosenfeld S, Srinivas S, Strope SA, Tward J, Twardowski P, Walsh PC, Ho M, Shead DA. [Advanced Prostate Cancer Consensus Conference (APCCC) 2015 in St. Gallen : Critical review of the recommendations on diagnosis and therapy of metastatic prostate cancer by a German expert panel]. Park SW, Hwang DS, Song WH, Nam JK, Lee HJ, Chung MK. A narrative review of pelvic lymph node dissection in prostate cancer. Radium-223 dichloride is a first-in-class radiopharmaceutical that recently received approval for treatment of patients with symptomatic bone metastases and no known visceral disease. NCCN recommendations for testing of prostate cancer tumors are as follows: Tumor testing for homologous recombination gene mutations (HRRm) and for microsatellite instability (MSI) … Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der Kwast T, Mason M, Matveev V, Wiegel T, Zattoni F, Mottet N; European Association of Urology. This report highlights notable recent updates. NCCN releases updated guidelines on management of prostate cancer Posted on February 20, 2018 by Sitemaster As it does at least once a year, the National Comprehensive Cancer Network (NCCN) has just released version 1.2018 of its guidelines for physicians on the management of prostate cancer. 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